Assassination rogues rely on poisons to deal damage, using Mutilate as their primary combo builder and Envenom as the finisher. The assassination DPS potential is behind combat in end game, however, it can compete or even pull ahead in lower gear brackets.

Rotation for Assassination Rogue Wotlk

Assassination Rogue Rotation and Priorities

Apply bleed with rupture if no one can > Hunger for Blood (Keep up) > Slice and Dice (First one with 2-3 combos) > Mutilate to 4-5 combo point > Envenom to refresh Slice and Dice

Tips

Never allow Hunger for Blood or Slice and Dice to drop.

Get to know the fights to pop cooldowns at the best times (low movement, no crowd control, AOE, etc).

Time cooldowns so they can be used to clean thrash and be ready at boss fights.

Avoid changing targets too much as combo reset on target change.

Use Vanish to increase energy regeneration from [Overkill] to increase DPS.