Assassination rogues rely on poisons to deal damage, using Mutilate as their primary combo builder and Envenom as the finisher. The assassination DPS potential is behind combat in end game, however, it can compete or even pull ahead in lower gear brackets.

Talents for Assassination Rogue Wotlk

Assassination Rogue Talents for Wotlk

Glyphs for Assassination Rogue Wotlk

Major

Glyph of Mutilate

Glyph of Hunger for blood

Glyph of Envenom

With Set T10 Set Bonus Bonus (Optional threat reduction, replaces Glyph of Envenom)

Glyph of Tricks of the Trade

Minor

Glyph of Vanish

Notes

The T10 bonus set gives 15 energy on use for Tricks of the Trade, however the Glyph will only increase your DPS if threat is an issue, so it can be beneficial to the raid, however it does not increase DPS directly, it will depend on own good the tanks are.